1. Epitranscriptomic regulation of mRNA stability in pivotal transcription factors modulates the second cell fate decision.

Xiao W, Tang L, Ma M, Liu K, Lu J, Ding W, Bai Z, Liu X, Kou X, Zhao Y, Wang H, Yang L, Gao S, Gao Y, Liu J. Nature communications. 2026 Apr;17(1). doi: 10.1038/s41467‑026‑72131‑2

[https://pubmed.ncbi.nlm.nih.gov/42045194/](https://pubmed.ncbi.nlm.nih.gov/42045194/)

2. The maternal PADI6‑UHRF1‑UBE2D complex regulates ubiquitination during oocyte maturation and embryogenesis.

Li J, Lu Y, Xia Z, Chi P, Qi Q, Liu S, Ju S, Li J, Zhang Z, Han Z, Liu Q, Meng W, Chen J, Wang X, Guo L, Li L, Huang W, Dai L, Han J, Gao S, Deng D. Nature structural & molecular biology. 2026 Mar;33(3):512‑524. doi: 10.1038/s41594‑026‑01758‑y

[https://pubmed.ncbi.nlm.nih.gov/41772195/](https://pubmed.ncbi.nlm.nih.gov/41772195/)

3. Single‑cell analysis reveals essential lncRNAs regulating human trophoblast lineage differentiation.

Zhang W, Le C, Yi S, Liu W, Liu X, Yin Z, Wang H, Gao R, Gao S, Chen J. Life medicine. 2026 Apr;5(2):lnag010. doi: 10.1093/lifemedi/lnag010

[https://pubmed.ncbi.nlm.nih.gov/42051595/](https://pubmed.ncbi.nlm.nih.gov/42051595/)

4. Zinc accumulation‑induced integrated stress response triggers β‑cell identity loss.

Ma Q, Xu W, Wang X, Nie H, Gao Y, Hu R, Yang Z, Wang X, Na T, Chen X, Wang Z, Xu M, Shao L, Guo M, Liu Y, Le R, Gao S, Li W. Cell research. 2026 May;36(5):359‑376. doi: 10.1038/s41422‑026‑01222‑y

[https://pubmed.ncbi.nlm.nih.gov/41606169/](https://pubmed.ncbi.nlm.nih.gov/41606169/)

5. Generation of modified cows and sheep from spermatid‑like haploid embryonic stem cells.

Yang L, Di A, Song L, Liu X, Wu D, Wang S, Hao Z, Bu L, Bai C, Su G, Wei Z, Zhang L, Liu Z, Gao S, Li G. Nature biotechnology. 2026 Aug;44(8):1361‑1369. doi: 10.1038/s41587‑025‑02832‑4

[https://pubmed.ncbi.nlm.nih.gov/41057660/](https://pubmed.ncbi.nlm.nih.gov/41057660/)

6. Distal enhancers regulate mammalian early embryonic lineage differentiation through long‑range interactions.

Zhu Q, Guo S, Xie J, Qu J, Wan X, Liang S, Liu X, Zhu L, Wang J, Yang S, Dong Q, Huang G, Gao S, Chen M, Li J. Nucleic acids research. 2026 Jan;54(2). doi: 10.1093/nar/gkag026

[https://pubmed.ncbi.nlm.nih.gov/41562256/](https://pubmed.ncbi.nlm.nih.gov/41562256/)

7. Rapid production of precisely edited cattle and mice via a single AAV delivered miniature IscB.

Song L, Liu X, Di A, Wu D, Bai C, Bu L, Pei D, Lei J, Hao Z, Su G, Zhao Y, Wei Z, Gao S, Li G, Yang L. Cell discovery. 2026 Mar;12(1). doi: 10.1038/s41421‑026‑00871‑y

[https://pubmed.ncbi.nlm.nih.gov/41844592/](https://pubmed.ncbi.nlm.nih.gov/41844592/)

8. Decoding adenomyosis pathogenesis using an assembloid model.

Xu Y, Cheng T, Wang J, Qiu Z, Guan X, Yu Y, Shen J, Xu F, Jiang X, Bai D, Wang M, Mei S, Wang H, Xu X, Wu L, Gao S, Che X. Science China. Life sciences. 2026 Jan;69(1):136‑150. doi: 10.1007/s11427‑025‑2981‑1

[https://pubmed.ncbi.nlm.nih.gov/40889046/](https://pubmed.ncbi.nlm.nih.gov/40889046/)

9. A Cytosine Deaminase‑Based Genomic Footprinting Assay (cFOOT‑seq) for Detecting Transcription Factor Occupancy.

Yang MC, Wu A, Wang H, Liu X, Shi J, Gao S, Zhang JM. Bio‑protocol. 2026 Mar;16(6):e5637. doi: 10.21769/BioProtoc.5637

[https://pubmed.ncbi.nlm.nih.gov/41924246/](https://pubmed.ncbi.nlm.nih.gov/41924246/)

10. Chaf1a is required for cardiomyocyte karyokinesis and cardiac endowment.

Ouyang Z, Yuan M, Huang R, Tang Y, Wang M, Yao Z, Shi G, Feng M, Chen J, Nie Y, Gao S, Xu D, Wei K. Protein & cell. 2026 Jul. doi: 10.1093/procel/pwag051

[https://pubmed.ncbi.nlm.nih.gov/42500988/](https://pubmed.ncbi.nlm.nih.gov/42500988/)

11. LncRNA Gas5 directs SUV39H2 to establish heterochromatin and maintain genome stability.

Liu J, Yang J, Ye W, Zhang D, Su N, Wang H, Zhang Y, Gao S, Kang L. Protein & cell. 2026 Jun. doi: 10.1093/procel/pwag039

[https://pubmed.ncbi.nlm.nih.gov/42334949/](https://pubmed.ncbi.nlm.nih.gov/42334949/)

12. PRDM14 promotes the bovine somatic stem cell reprogramming through enhancing oxidative phosphorylation at the initial stage.

Wei Q, Li W, Cui G, Xu Y, Gao S. Gene. 2026 Mar;982:149978. doi: 10.1016/j.gene.2025.149978

[https://pubmed.ncbi.nlm.nih.gov/41448293/](https://pubmed.ncbi.nlm.nih.gov/41448293/)

13. PKM1 is required for embryonic cardiomyocyte proliferation through energetic regulation of NFYa stability.

Zhang D, Tang Y, Ye W, Yang D, Qin S, Liu J, Su N, Huang R, Shi G, Xu D, Kou X, Zhao Y, Wang H, Gao S, Wei K, Kang L. National science review. 2026 Jan;13(1):nwaf408. doi: 10.1093/nsr/nwaf408

[https://pubmed.ncbi.nlm.nih.gov/41536305/](https://pubmed.ncbi.nlm.nih.gov/41536305/)

14. Generating LGE/CGE Organoids from Human Pluripotent Stem Cell‑derived Brain Organoids Without External Signal Induction.

Zhu X, Bai Z, Ren Y, Chang Z, Wang Y, Li P, Liang Y, Zhao Z, Zhu Y, Gao S, Gao Y, Chen X. Cell reports. 2026 Jan;45(1):116780. doi: 10.1016/j.celrep.2025.116780

[https://pubmed.ncbi.nlm.nih.gov/41485221/](https://pubmed.ncbi.nlm.nih.gov/41485221/)

15. Endogenous retroviruses synthesize heterologous chimeric RNAs to reinforce human early embryo development.

Xiang Y, Qian Y, Li Z, Wang J, Tian R, Meng W, Bu J, Huang F, Ai Z, Wu D, Chen X, Wu Y, Shen L, Chan YS, Gao Y, Ma J, Liu W, Gao S, Zhang D, Liang H. Science. 2026 Jan;391(6783):eadv5257. doi: 10.1126/science.adv5257

[https://pubmed.ncbi.nlm.nih.gov/41570148/](https://pubmed.ncbi.nlm.nih.gov/41570148/)

16. Gaseous liquid nitrogen‑assisted cryo‑printing strategies for challenging volumetric anisotropic tissues fabrication.

Gao Z, Li W, Luo Z, Liu X, Zhang Z, Tu X, Li H, Liu Z, Li S, Xu X, Wang H, Gao S, Yin F, Wang M. Science advances. 2026 Aug;12(32):eadz1325. doi: 10.1126/sciadv.adz1325

[https://pubmed.ncbi.nlm.nih.gov/42566548/](https://pubmed.ncbi.nlm.nih.gov/42566548/)

17. Genome‑wide profiling of histone modifications and transcription factor binding at single‑cell resolution by DeChIC‑seq.

Shi Z, Chen X, Yang Y, Wu A, Wang H, Chen K, Li C, Zou L, Qu Z, Zhao Y, Gan W, Li S, Chen J, Liu W, Shi J, Wang H, Zhang JM, Wang C, Gao S, Liu X. Cell research. 2026 Jul. doi: 10.1038/s41422‑026‑01275‑z

[https://pubmed.ncbi.nlm.nih.gov/42443520/](https://pubmed.ncbi.nlm.nih.gov/42443520/)

18. Corrigendum to Fatty acid oxidase Ehhadh mediates stem cell fate remodeling via mitophagy activation [Free Radic. Biol. Med. 248 (2026) 109‑126].

Zhou J, Zhang L, Liu T, Sun J, Sun Y, Gao S, Shi K. Free radical biology & medicine. 2026 Oct;254:871‑873. doi: 10.1016/j.freeradbiomed.2026.06.057

[https://pubmed.ncbi.nlm.nih.gov/42401507/](https://pubmed.ncbi.nlm.nih.gov/42401507/)

19. Lipid metabolic remodeling shapes early human maternal‑embryo interface function.

Zhang X, Xu Y, Wang X, Yan Z, Hu J, Wang R, Liu Y, Zhang Y, Wu L, Wang H, Gao S, Wang Y. Science bulletin. 2026 Aug;71(15):3848‑3852. doi: 10.1016/j.scib.2026.05.024

[https://pubmed.ncbi.nlm.nih.gov/42230248/](https://pubmed.ncbi.nlm.nih.gov/42230248/)

20. Autophagy‑dependent disruption of β‑FAO‑mediated histone acetylation in embryos during maternal aging.

Deng D, Li C, Zhu L, Tian Y, Wang J, Li C, Chen M, Huang G, Gao S, Guo S, Li J. Science bulletin. 2026 May;71(10):2413‑2417. doi: 10.1016/j.scib.2026.02.053

[https://pubmed.ncbi.nlm.nih.gov/41927372/](https://pubmed.ncbi.nlm.nih.gov/41927372/)

21. DDX5 orchestrates RNA homeostasis to ensure oocyte developmental competence.

Wang M, Wang L, Cai Q, Huang Y, Yi S, Pan H, Liu W, Wang H, Yao H, Jiang C, Gao S, Chen J. Nature communications. 2026 Mar;17(1). doi: 10.1038/s41467‑026‑70237‑1

[https://pubmed.ncbi.nlm.nih.gov/41813665/](https://pubmed.ncbi.nlm.nih.gov/41813665/)

22. Fatty acid oxidase Ehhadh mediates stem cell fate remodeling via mitophagy activation.

Zhou J, Zhang L, Liu T, Sun J, Sun Y, Gao S, Shi K. Free radical biology & medicine. 2026 May;248:109‑126. doi: 10.1016/j.freeradbiomed.2026.02.046

[https://pubmed.ncbi.nlm.nih.gov/41724368/](https://pubmed.ncbi.nlm.nih.gov/41724368/)

23. Steering semi‑flexible molecular diffusion model for structure‑based drug design with reinforcement learning.

Zhang X, Qu S, Lu F, Wang J, Tian Z, Gu S, Zhang Y, Knoll A, Gao S, Chen G, Jiang C. Science advances. 2026 Apr;12(16):eady9955. doi: 10.1126/sciadv.ady9955

[https://pubmed.ncbi.nlm.nih.gov/41984966/](https://pubmed.ncbi.nlm.nih.gov/41984966/)