2020年
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1. DUX-miR-344-ZMYM2-Mediated Activation of MERVL LTRs Induces a Totipotent 2C-like State. 

Yang F, Huang X, Zang R, Chen J, Fidalgo M, Sanchez-Priego C, Yang J, Caichen A, Ma F, Macfarlan T, Wang H, Gao S, Zhou H, Wang J. 

Cell Stem Cell. 2020 Feb 6;26(2):234-250.e7. doi: 10.1016/j.stem.2020.01.004.

https://pubmed.ncbi.nlm.nih.gov/32032525/


2. Insights into epigenetic patterns in mammalian early embryos. 

Xu R, Li C, Liu X, Gao S.

Protein Cell. 2020 Jul 15. doi: 10.1007/s13238-020-00757-z. 

https://pubmed.ncbi.nlm.nih.gov/32671792/


3. Chromatin architecture reorganization in murine somatic cell nuclear transfer embryos.

Chen M, Zhu Q, Li C, Kou X, Zhao Y, Li Y, Xu R, Yang L, Yang L, Gu L, Wang H, Liu X, Jiang C, Gao S.

Nat Commun. 2020 Apr 14;11(1):1813. doi: 10.1038/s41467-020-15607-z.

https://pubmed.ncbi.nlm.nih.gov/32286279/


4. A high-throughput small molecule screen identifies farrerol as a potentiator of CRISPR/Cas9-mediated genome editing.

Zhang W, Chen Y, Yang J, Zhang J, Yu J, Wang M, Zhao X, Wei K, Wan X, Xu X, Jiang Y, Chen J, Gao S, Mao Z. 

Elife. 2020 Jul 9;9:e56008. doi: 10.7554/eLife.56008.

https://pubmed.ncbi.nlm.nih.gov/32644042/


5. Identification of ALPPL2 as a Naive Pluripotent State-Specific Surface Protein Essential for Human Naive Pluripotency Regulation.

Bi Y, Tu Z, Zhang Y, Yang P, Guo M, Zhu X, Zhao C, Zhou J, Wang H, Wang Y, Gao S.

Cell Rep. 2020 Mar 17;30(11):3917-3931.e5. doi: 10.1016/j.celrep.2020.02.090.

https://pubmed.ncbi.nlm.nih.gov/32187559/


6. Lessons from expanded potential of embryonic stem cells: Moving toward totipotency.

Le R, Huang Y, Zhao A, Gao S.

J Genet Genomics. 2020 Mar 20;47(3):123-130. doi: 10.1016/j.jgg.2020.02.003. Epub 2020 Mar 7.

https://pubmed.ncbi.nlm.nih.gov/32305172/


7. Reprogramming competence of OCT factors is determined by transactivation domains.

Kim KP, Wu Y, Yoon J, Adachi K, Wu G, Velychko S, MacCarthy CM, Shin B, Röpke A, Arauzo-Bravo MJ, Stehling M, Han DW, Gao Y, Kim J, Gao S, Schöler HR.

Sci Adv. 2020 Sep 2;6(36):eaaz7364. doi: 10.1126/sciadv.aaz7364. Print 2020 Sep.

https://pubmed.ncbi.nlm.nih.gov/32917606/


8. Precise allele-specific genome editing by spatiotemporal control of CRISPR-Cas9 via pronuclear transplantation.

Li Y, Weng Y, Bai D, Jia Y, Liu Y, Zhang Y, Kou X, Zhao Y, Ruan J, Chen J, Yin J, Wang H, Teng X, Wang Z, Liu W, Gao S.

Nat Commun. 2020 Sep 14;11(1):4593. doi: 10.1038/s41467-020-18391-y.

https://pubmed.ncbi.nlm.nih.gov/32929070/


9.  Identification and rescue of a novel TUBB8 mutation that causes the first mitotic division defects and infertility.

Jia Y, Li K, Zheng C, Tang Y, Bai D, Yin J, Chi F, Zhang Y, Li Y, Tu Z, Wang Y, Pan J, Liang S, Guo Y, Ruan J, Kong P, Wu B, Hu Y, Wang H, Liu W, Teng X, Gao S. 

J Assist Reprod Genet. 2020 Nov;37(11):2713-2722. doi: 10.1007/s10815-020-01945-w. Epub 2020 Sep 18.

https://pubmed.ncbi.nlm.nih.gov/32949002/


10. Genome transfer for the prevention of female infertility caused by maternal gene mutation.

Bai D, Sun J, Jia Y, Yin J, Zhang Y, Li Y, Gao R, Du X, Li K, Lin J, Tu Z, Wang Y, Pan J, Liang S, Guo Y, Ruan J, Kou X, Zhao Y, Wang H, Jiang C, Wang F, Teng X, Liu W, Gao S.

J Genet Genomics. 2020 Jun 20;47(6):311-319. doi: 10.1016/j.jgg.2020.06.002. Epub 2020 Jun 21

https://pubmed.ncbi.nlm.nih.gov/32893179/


11. The SIRT6 activator MDL-800 improves genomic stability and pluripotency of old murine-derived iPS cells.

Yu Chen, Jiayu Chen, Xiaoxiang Sun, Jiayu Yu, Zhen Qian, Li Wu, Xiaojun Xu, Xiaoping Wan, Ying Jiang, Jian Zhang, Shaorong Gao, Zhiyong Mao.

Aging Cell. 2020 Aug;19(8):e13185. doi: 10.1111/acel.13185. Epub 2020 Jul 21.

https://pubmed.ncbi.nlm.nih.gov/33089974/


12. Dux-Mediated Corrections of Aberrant H3K9ac during 2-Cell Genome Activation Optimize Efficiency of Somatic Cell Nuclear Transfer.

Yang G, Zhang L, Liu W, Qiao Z, Shen S, Zhu Q, Gao R, Wang M, Wang M, Li C, Liu M, Sun J, Wang L, Liu W, Cui X, Zhao K, Zang R, Chen M, Liang Z, Wang L, Kou X, Zhao Y, Wang H, Wang Y, Gao S, Chen J, Jiang C.

Cell Stem Cell. 2020 Oct 5:S1934-5909(20)30452-5. doi: 10.1016/j.stem.2020.09.006. Online ahead of print.

https://pubmed.ncbi.nlm.nih.gov/33049217/


13.  A DNA methylation state transition model reveals the programmed epigenetic heterogeneity in human pre-implantation embryos.

Zhao C, Zhang N, Zhang Y, Tuersunjiang N, Gao S, Liu W, Zhang Y.

Genome Biol. 2020 Nov 16;21(1):277. doi: 10.1186/s13059-020-02189-8.

https://pubmed.ncbi.nlm.nih.gov/33198783/


14. N 6-methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription.

Liu J, Dou X, Chen C, Chen C, Liu C, Xu MM, Zhao S, Shen B, Gao Y, Han D, He C.

Science. 2020 Jan 31;367(6477):580-586. doi: 10.1126/science.aay6018. Epub 2020 Jan 16.

https://pubmed.ncbi.nlm.nih.gov/31949099/




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