1.CD47-blocking antibody confers metabolic benefits against obesity.

Su Y, Sun J, Li X, Huang F, Kong Y, Chen Z, Zhang J, Qin D, Chen X, Wang Z, Pei Y, Gong M, Yang K, Xu M, Dong Y, He Q, Zhang ZN, Sheng Z, Deng Q, Wang H, Wang G, Hu P, Le R, Gao S, Li W. CD47-blocking antibody confers metabolic benefits against obesity. Cell Rep Med. 2025 May 20;6(5):102089. doi: 10.1016/j.xcrm.2025.102089. Epub 2025 Apr 22. PMID: 40267910; PMCID: PMC12147847.

2.Acetylation at lysine 27 on maternal H3.3 regulates minor zygotic genome activation.

Zhang J, Li X, Zhao Q, Ji J, Cui H, Hou W, Wang X, Song E, Xiao S, Ling S, Gao S, Liu X, Wen D, Kong Q. Acetylation at lysine 27 on maternal H3.3 regulates minor zygotic genome activation. Cell Rep. 2025 Jan 28;44(1):115148. doi: 10.1016/j.celrep.2024.115148. Epub 2024 Dec 31. PMID: 39932187; PMCID: PMC11892348.

3.Setd2 overexpression rescues bivalent gene expression during SCNT-mediated ZGA.

Zhang X, Xu R, Zhao Y, Yang Y, Shi Q, Wang H, Liu X, Gao S, Li C. Setd2 overexpression rescues bivalent gene expression during SCNT-mediated ZGA. Protein Cell. 2025 Feb 13:pwaf010. doi: 10.1093/procel/pwaf010. Epub ahead of print. PMID: 39945726.

4.Core factor of NEXT complex, ZCCHC8, governs the silencing of LINE1 during spermatogenesis.

Yan R, Qi M, Zhang P, Shen B, Yin J, Chen C, Tian S, Chen L, Huang X, Wang H, Gao S, Wu Y, Gao Y. Core factor of NEXT complex, ZCCHC8, governs the silencing of LINE1 during spermatogenesis. Natl Sci Rev. 2024 Dec 17;12(1):nwae407. doi: 10.1093/nsr/nwae407. PMID: 39758125; PMCID: PMC11697976.

5.Maternal infection with SARS-CoV-2 during early pregnancy induces hypoxia at the maternal-fetal interface.

Shi X, Xi C, Dong B, Yan Z, Liu W, Gao S, Chen D. Maternal infection with SARS-CoV-2 during early pregnancy induces hypoxia at the maternal-fetal interface. Cell Prolif. 2025 Feb;58(2):e13749. doi: 10.1111/cpr.13749. Epub 2024 Oct 7. PMID: 39375953; PMCID: PMC11839197.

6.Inhibition of aging-induced DNA hypermethylation by si-Dnmt3a/3b in pre-implantation embryos improves aberrant social behavior in offspring.

Liu YD, Teng XM, Bai DD, Xing FY, Chang QR, Li JL, Gao SR, Liu WQ, Guo Y. Inhibition of aging-induced DNA hypermethylation by si-Dnmt3a/3b in pre-implantation embryos improves aberrant social behavior in offspring. Int J Biol Macromol. 2025 May;307(Pt 4):142130. doi: 10.1016/j.ijbiomac.2025.142130. Epub 2025 Mar 17. PMID: 40107549.

7.Epigenetic regulation in early embryo development: from zygotic genome activation to the first lineage specification.

Xu R, Li Y, Wu Y, Liu X, Gao S. Epigenetic regulation in early embryo development: from zygotic genome activation to the first lineage specification. Trends Genet. 2025 Jun 5:S0168-9525(25)00112-X. doi: 10.1016/j.tig.2025.05.005. Epub ahead of print. PMID: 40480920.

8.Persistent Wnt signaling affects IVF embryo implantation and offspring metabolism.

Jia Y, Liu Y, Li Y, Guan X, Xu J, Yan Z, Liu K, Zhang Y, Bai D, Xiang J, Zhang Y, Hou S, Kou X, Zhao Y, Yin J, Wang H, Li K, Gao S, Liu W. Persistent Wnt signaling affects IVF embryo implantation and offspring metabolism. Sci Bull (Beijing). 2025 May 8:S2095-9273(25)00472-4. doi: 10.1016/j.scib.2025.05.003. Epub ahead of print. PMID: 40441968.

9.Altered 3D genome reorganization mediates precocious myeloid differentiation of aged hematopoietic stem cells in inflammation.

Cui X, Dong Y, Zhan Q, Huang Y, Zhu Q, Zhang Z, Yang G, Wang L, Shen S, Zhao J, Lin Z, Sun J, Su Z, Xiao Y, Zhang C, Liang Y, Shen L, Ji L, Zhang X, Yin J, Wang H, Chen Z, Ju Z, Jiang C, Le R, Gao S. Altered 3D genome reorganization mediates precocious myeloid differentiation of aged hematopoietic stem cells in inflammation. Sci China Life Sci. 2025 May;68(5):1209-1225. doi: 10.1007/s11427-024-2754-9. Epub 2024 Dec 27. PMID: 39754007.