姓名：张燕 

邮箱：23310141@tongji.edu.cn

研究方向：干细胞多能性、全能性命运调控机制研究与早期胚胎发育

教育与工作经历:

2023.07-至今             同济大学                 博士后

2020.09-2023.06          安徽大学                 生态学（博士）

2016.09-2019.06          安徽大学                 细胞生物学（硕士）

2011.09-2015.06  泰山医学院（现山东第一医科大学） 生物工程（学士）

主要科研成果为（*共同第一作者）：

1.Zhang Y*, Ding H*, Wang X*, Wang X*, Wan S, Xu A, Gan R, Ye SD. MK2 promotes Tfcp2l1 degradation via β-TrCP ubiquitin ligase to regulate mouse embryonic stem cell self-renewal. Cell Reports. 2021,37(5):109949. 

2.Zhu Z*, Zhang Y*, Wang X*, Wang X*, Ye SD. Inhibition of protein kinase D by CID755673 promotes maintenance of the pluripotency of embryonic stem cells. Development. 2020,147(16):dev185264. 

3.Zhang Y, Ding H, Wang X, Ye SD. Modulation of STAT3 phosphorylation by PTPN2 inhibits naïve pluripotency of embryonic stem cells. FEBS Letters. 2018,592(13): 2227-2237.

4.Zhang Y, Zhu Z, Ding H, Wan S, Zhang X, Li Y, Ji J, Wang X, Zhang M, Ye SD. β-catenin stimulates Tcf7l1 degradation through recruitment of casein kinase 2 in mouse embryonic stem cells. Biochemical and Biophysical Research Communications. 2020 ,524(2):280-287. 

5.Zhang M*, Ji J*, Wang X*, Zhang X*, Zhang Y*, Li Y, Wang X, Li X, Ban Q, Ye SD. The transcription factor Tfcp2l1 promotes primordial germ cell-like cell specification of pluripotent stem cells. Journal of Biological Chemistry. 2021,297(4):101217. 

6.Wang X*, Wang X*, Zhang X*, Zhang Y*, Zhu Z, Li Y, Zhang M, Ji J, Yu Y, Ye SD. Inhibition of ubiquitin-specific protease 13-mediated degradation of Raf1 kinase by Spautin-1 has opposing effects in naïve and primed pluripotent stem cells. Journal of Biological Chemistry. 2021, 297(5):101332.